Many women experience significant mood changes during perimenopause and menopause, including increased irritability, tearfulness, low mood, and emotional volatility that can feel completely out of character. These changes are largely driven by fluctuating oestrogen levels affecting serotonin and other mood-regulating brain chemicals, and they have a genuine physiological basis — this is not “just stress” or simply getting older.
Perimenopausal women face a significantly elevated risk of depression compared to premenopausal women. At The York Clinic, we understand how isolating and distressing these symptoms can feel. Our menopause specialists take a compassionate, whole-person approach, exploring whether HRT, non-hormonal options, lifestyle changes, or a combination of treatments can help you feel more like yourself again. You deserve to feel well — and we are here to help make that happen.
